Cytoplasmic Transfer


IVF Treatment with Cytoplasmic Transfer

Target Patient Group

Female patients in their early 40s with diminished ovarian reserves and compromised oocyte quality with the possibility of damages mitochondria in the egg cell’s cytoplasm.

Success Rates

Success rates with Cytoplasmic transfer differ among different age brackets and patients with differing ovarian reserves. However, cytoplasmic transfer is likely to add 4-5% to the rate of success with standard IVF+ICSI treatments.

Cost of Treatment

Please contact us for more details on the cost of our IVF with cytoplasmic transfer treatment.

Length of Stay in Cyprus

You are expected to stay in Cyprus for 5/6 days to finalize your treatment. You will be able to have your preliminary work done locally under our supervision and guidance.

Cytoplasmic transfer is one of the latest innovations in IVF treatment. Cytoplasmic transfer in itself is not a treatment method, but rather is a procedure that is used in combination with IVF/ICSI treatment.  The main purpose of cytoplasmic transfer is to help older women who are likely to suffer from infertility due to deficient or damaged mitochondria, contained within an eggs cytoplasm.  Mitochondria found in the egg’s cytoplasm are responsible for providing the necessary energy for cell growth and effective cell division. Deficient mitochondria, therefore, will be unable to perform its duties and will not allow for successful cell growth and/or cell division. This can lead to recurrent implantation failures and high levels of embryo fragmentation, which are causes of poor embryo quality and poor embryo development, and therefore,  an IVF failure.


Just like organ failures and cell damage, damage to mitochondria is observed in higher age brackets, therefore, women in early 40s are more      prone to IVF failures due to damaged mitochondria compared to women in early ages. The difference between a regular IVF/ICSI cycle and the one which involves a cytoplasmic transfer is that, cytoplasmic transfer uses the patient’s own eggs, just like in an IVF cycle, but also requires an egg donor since the healthy mitochondria are to be obtained from young and healthy eggs to be obtained from an egg donor. The younger egg donor’s cytoplasm contains healthy mitochondria and helps rejuvenate the patient’s eggs and can increase the chances of success accordingly. The main principle is, if the patient’s eggs are given a more friendly environment to grow in (donor’s cytoplasm), then the egg will have a better chance to survive, fertilize and become a higher quality embryo. In other words, the patient is more likely to achieve success with her own eggs when her egg cells are given a better environment to grow, fertilize and to yield a higher grade embryo.

IVF with Cytoplasmic Transfer offers higher success rates

At North Cyprus IVF, we have been offering cytoplasmic transfer to our patients since 2012. Within the two year period, we have offered this treatment to a number of patients, however, the number is still insufficient for publishing statistically significant statistics. However, it will be correct to say that cytoplasmic transfer can potentially add a few percentages to the chances of success for women in their early 40s. Nevertheless, it should be kept in mind that cytoplasmic transfer is unable to correct for any genetic defects associated with the eggs themselves that may have arisen due to older age.

Cytoplasmic transfer is a procedure we recommend patients in their early to mid 40s. However, after mid 40s, chances of success with own eggs will decline substantially, therefore, we often recommend our patients to consider Donor Egg IVF treatment after a certain age.

At North Cyprus IVF, we guarantee high quality treatment with maximum service quality standards at low cost. Our reduced costs are a direct result of the volume of patients we serve and the high-tech equipment we use which substantially reduce human mistakes and allow us to be cost efficient. For a quote, please send us a message using the Contact us

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